There are multiple universes in the YKWTNI series.
List of Universes
-Main universe: This is the universe in which all of the canon You'll Know What to Name it movies are set in.
-Darkshadow universe: Brian O'Connor is created by a mad scientist as "Darkshadow." Darkshadow defeats a villain called Crazed Mask and escapes the mad scientist, and then becomes an anti-hero.
-Ace 2 universe: Brian O'Connor keeps the alias "Ace" and travels to another universe through a machine to stop an alternate version of himself and Gary. He never meets John Sniper and dies of a rare disease a few years after his universe-travelling mission.
-Swapped universe: This is the universe "Ace" travels to in Ace 2. Brian's and Gary's personalities and part of their outfits(among other things) are swapped. Their names are Gary O'Connor and Brian the Guy. They are both defeated by Ace 2 Brian.
-Susan universe: Brian's best friend from 20 years ago, Susan, survives from whatever she dies from in the main universe and, after Brian rescues her from Gary the Guy , the two and an auctioneer live happily ever after together.
-Space universe: 30 years after the event of all the episodes in the main universe, space travel is quite popular but no one cares because that's lame. But when an army of Teletubbies and Disney people, along with T-series supporters, invade Plexi'Qwa, Brian is chosen to lead a resistance to defeat them and travels around the solar system defeating the villains. Paul becomes president of the world, Steve gets married, Trouty becomes a unicorn, John Sniper becomes obese, I Know Right is still alive as a fat Russian dude, and Gary, who is also fat, reforms in jail - and dies there, and Brian eventually blows up. Wierd.
